pentobarbital will lower the extent or result of alfuzosin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.pentobarbital decreases amounts of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers can reduce panobinostat degrees by ~70% and cau